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Immune gene therapy as a neoadjuvant to surgical excision to control metastatic cancers, Cancer Letters | 10.1016/j.canlet.2007.11.042 | DeepDy

Read "Immune gene therapy as a neoadjuvant to surgical excision to control metastatic cancers, Cancer Letters" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.

Neoadjuvant systemic therapy in melanoma: recommendations of the International Neoadjuvant Melanoma Consortium - ScienceDire

A continuum of pathological responses has been observed in patients with melanoma treated with neoadjuvant targeted therapy or immune checkpoint therapy. Pathological complete response is defined as the complete absence of residual viable tumour. ...

Current Status and Future Perspectives on Neoadjuvant Therapy in Lung Cancer - ScienceDire

This Review Article provides a multi-stakeholder view on the current status of neoadjuvant therapy in lung cancer. ... Initial experiences in small numbers of patients with neoadjuvant chemotherapy and immune checkpoint inhibitors (n = 14) suggested activity and ...

Phase I neoadjuvant study of intravesical recombinant fowlpox-GM-CSF (rF-GM-CSF) or fowlpox-TRICOM (rF-TRICOM) in patients with bladder carcinoma .

Phase I neoadjuvant study of intravesical recombinant fowlpox-GM-CSF (rF-GM-CSF) or fowlpox-TRICOM (rF-TRICOM) in patients ... Mastrangelo MJ, Lattime EC. Intravesical gene therapy: in vivo gene transfer using recombinant vaccinia virus vectors. Cancer ...

The 41-gene classifier TRAR predicts response of HER2 positive breast cancer patients in the NeoALTTO study - ScienceDire

Tumors with TRAR low scores were found enriched of immune-related features. Abstract Background Dual HER2-inhibition combined with neoadjuvant chemotherapy allows increased pathological complete response (pCR) rate. ...

Impact of Immune and Stromal Infiltration on Outcomes Following Bladder-Sparing Trimodality Therapy for Muscle-Invasive Bladder Canc

tested the association of immune and stromal gene signatures with clinically relevant end-points. 2. Patients and methods 2.1. ... associated with an improved response to radiation therapy. Using a T-cell-inflamed gene expression signature that has ...

Metronomics in the neoadjuvant and adjuvant treatment of breast cancer - ScienceDire

Metronomics in the neoadjuvant and adjuvant treatment of breast cancer Author links open overlay panel Elisabetta Munzone Marco ... neoadjuvant therapy gives also the opportunity to obtain tumor specimens and blood samples before and during the ...

Virus Specific Immune Responses after Human Neoadjuvant Adenovirus-mediated Suicide Gene Therapy for Prostate Cancer - ScienceDire

Volume 48, Issue 1, July 2005, Pages 153-161

Current Status and Future Perspectives on Neoadjuvant Therapy in Lung Cancer - Journal of Thoracic Oncolo

This Review Article provides a multi-stakeholder view on the current status of neoadjuvant therapy in lung cancer. ... Initial experiences in small numbers of patients with neoadjuvant chemotherapy and immune checkpoint inhibitors (n = 14) suggested activity and ...

Immune gene therapy as a neoadjuvant to surgical excision to control metastatic cancers, Cancer Letters | 10.1016/j.canlet.2007.11.042 | DeepDy

Read "Immune gene therapy as a neoadjuvant to surgical excision to control metastatic cancers, Cancer Letters" on DeepDyve, the largest online rental service for scholarly research with thousands of academic publications available at your fingertips.

Immune gene therapy as a neoadjuvant to surgical excision to control metastatic cancers | J.P. Cashman | Request P

Request PDF on ResearchGate | Immune gene therapy as a neoadjuvant to surgical excision to control metastatic cancers | We investigated if the range of efficacy of a gene-based immunotherapy of solid tumours against systemic disease could be extended when ...

Neoadjuvant pembrolizumab in bladder cancer - The Lancet Oncolo

Pembrolizumab might be an effective neoadjuvant therapy for the treatment of muscle-invasive bladder cancer—especially in patients with programmed death-ligand 1 (PD-L1)-positive or high mutation burden tumours—according to a recent study.

Inflammation, Apoptosis, and Necrosis Induced by Neoadjuvant Fas Ligand Gene Therapy Improves Survival of Dogs With Spontaneous Bone Cancer .

Fas ligand (FasL) gene therapy for cancer has shown promise in rodents; however, its efficacy in higher mammals remains unknown. Here, we used intratumoral FasL gene therapy delivered in an adenovirus vector (Ad-FasL) as neoadjuvant to standard of care in 56 ...

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Immune gene therapy as a neoadjuvant to surgical excision to control metastatic cancers Status Validated Times Cited () Optional Fields Keywords Volume 262 Issue 11 Start Page 94 End Page 10294 Abstract We investigated if the range of efficacy used as a ...

Anti-tumor immune responses following neoadjuvant immunotherapy with a recombinant adenovirus expressing HSP72 to rodent tumors. | PubFac

Cancer Immunol Immunother 2005 Oct 12;54(10):988-98. Epub 2005 May 12. Center for Anatomic Studies, Saint Louis University, USA.

Virus specific immune responses after human neoadjuvant adenovirus-mediated suicide gene therapy for prostate cance

Virus specific immune responses after human neoadjuvant adenovirus-mediated suicide gene therapy for prostate cancer. van der Linden RR(1), Haagmans BL, Mongiat-Artus P, van ...

Virus Specific Immune Responses after Human Neoadjuvant Adenovirus-mediated Suicide Gene Therapy for Prostate Cancer - European Urolo

Neoadjuvant gene therapy potentially improves the outcome of primary treatment of prostate cancer by radical prostatectomy in patients with high risk of recurrence. We conducted a Phase I escalating dose study with a replication-defective adenovirus expressing the ...

Neoadjuvant anti-PD-1 immunotherapy promotes a survival benefit with intratumoral and systemic immune responses in recurrent glioblastoma | Nature .

Amaria, R. N. et al. Neoadjuvant immune checkpoint blockade in high-risk resectable melanoma. Nat. Med. 24, 1649–1654 (2018). CAS Article Google Scholar 21. ...

Pembrolizumab as Neoadjuvant Therapy Before Radical Cystectomy in Patients With Muscle-Invasive Urothelial Bladder Carcinoma (PURE-01): An Open .

Pembrolizumab as Neoadjuvant Therapy Before Radical Cystectomy in Patients With Muscle-Invasive Urothelial Bladder Carcinoma (PURE-01): An Open-Label, Single-Arm, ...

Virus Specific Immune Responses after Human Neoadjuvant Adenovirus-mediated Suicide Gene Therapy for Prostate Cancer - ScienceDire

Neoadjuvant gene therapy potentially improves the outcome of primary treatment of prostate cancer by radical prostatectomy in patients with high risk of recurrence. ...

Tumour-infiltrating lymphocytes and prognosis in different subtypes of breast cancer: a pooled analysis of 3771 patients ...- ScienceDire

For neoadjuvant therapy response, we observed a consistent positive association of increased TILs with increased pathological complete response. ...